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MGC premier ORF Clones

MGC premier ORF libraries


MGC premier ORF Libraries are genome-scale Gateway-adapted collections developed by the Dana Farber Cancer Institute-Center for Cancer Systems Biology (CCSB Human ORFeome Collection) using the most rigorous sequencing process ensuring the highest sequence quality and confidence.
  • Complete whole genome collections
  • Extended ORFeome v8.1 Library available
  • Lentiviral ORF library - includes over 13,000 ORFs
  • Available with or without stop codons

MGC premier human ORFeome Collaboration Library
MGC premier human ORFeome Collaboration Library currently represents 9,804 genes with 16,581 clones. The majority of the ORFeome collaboration targets were generated by the Dana Farber Cancer Institute-Center for Cancer Systems Biology (DFCI-CCSB). These full-length, annotated and sequence verified ORFs originate from the existing collection of MGC premier full-length human cDNA clones and have been transferred into Gateway Entry vectors as a ready to use resource for recombinant protein expression. For additional convenience and versatility the ORF clones are available in two formats, with and without stop codons. The ORF clones without stop codons facilitate the synthesis of either C- or N- terminal fusion proteins and clones with stop codons enable the synthesis of native proteins in addition to N-terminal fusion proteins.

The MGC premier ORFeome Collaboration Collection is also available for the mouse genome and represents 1,434 genes with 1,956 clones.

MGC premier human ORFeome v8.1 Library
MGC premier human ORFeome version 8.1 (hORFeome v8.1) is the newest version of the human ORFeome developed by the Center for Cancer Systems Biology (CCSB). This collection is derived from the Mammalian Gene Collection (MGC) and contains over 12,071 clonally-derived ORFs that represent 11,016 human genes. Each ORF clone in the collection has been verified by next generation sequencing and is provided in Gateway adapted entry vector for fast and convenient transfer to any compatible expression vector.

MGC premier Human ORFeome Complete Library - ORFeome Collaboration Collection + ORFeome v8.1 Library
MGC premier human ORFeome Complete Collection is our most extensive entry ORF library and includes both the ORFeome v8.1 and ORFeome Collaboration Collections. This collection provides unique, non-overlapping content and represents 14,918 genes with 22,057 clones.

MGC premier Lentiviral ORF Expression Library
This human Lentiviral ORF Expression Library was developed through the collaborative efforts of Dana-Farber Cancer Institute, The Broad Institute and the Center for Cancer Systems Biology (CCSB). The collection, which includes over 13,000 ORFs that represent approximately 11,373 genes, provides the most fully sequenced and annotated version of the human ORFeome available. For added convenience the lentiviral ORF expression vector was created to enable expression of a protein of interest with a V5 fusion tag for western blot detection, puri­fication, co-immunoprecipitation, protein localization and FACS analysis.

MGC premier ORF Libraries

Cat# Species Format Family Genes Literature Price Buy
TOH3507 Human Glycerol stock MGC premier human ORFeome Collaboration Library 9,804 View Request Pricing Contact Distributor
TOH3506 Human Glycerol stock MGC premier human ORFeome v8.1 Library 11,016 View Request Pricing Contact Distributor
TOH3505 Human Glycerol stock MGC premier human ORFeome Complete Library - (TOH3507 + TOH3506) 14,918 View Request Pricing Contact Distributor
TOH7500 Human Glycerol stock MGC premier Human Lentiviral ORF Library 11,373 View Request Pricing Contact Distributor
TOM3510 Mouse Glycerol stock MGC premier Mouse ORFeome Collaboration Library 1,434 View Request Pricing Contact Distributor

MGC premier Lentiviral ORF Gene Family and Pathway Libraries

Cat# Species Format Family Genes Literature Price Buy
TOH7505 Human Glycerol stock Apoptosis 206 View Request Pricing Contact Distributor
TOH7507 Human Glycerol stock Deubiquitinases 22 View Request Pricing Contact Distributor
TOH7506 Human Integral Membrane Proteins 2145 View Request Pricing Contact Distributor
TOH7501 Human Glycerol stock Kinase 364 View Request Pricing Contact Distributor
TOH7503 Human Mitochondrial proteins 606 View Request Pricing Contact Distributor
TOH7502 Human Glycerol stock Transcription factors 159 View Request Pricing Contact Distributor
TOH7504 Human Glycerol stock Ubiquitin Ligase 86 View Request Pricing Contact Distributor