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lncRNA Knockdown

lncRNA Knockdown Service

lncRNA knockdown is now possible with shERWOOD-UltramiR shRNA designs

Long non-coding RNAs (lncRNAs) are a type of non-coding RNAs (ncRNAs) that exceed 200 nucleotides in length. lncRNAs are involved in transcriptional regulation, post-transcriptional regulation events such as splicing and translation, epigenetic regulation and nucleation of protein complexes. Using a technique known as lncRNA knockdown, researchers are able to study lncRNA function by suppressing its expression and observing resulting phenotypes. The endogenous lncRNA expression can be down-regulated with an RNA silencing-mediated approach by stably expressing gene-specific RNA hairpins (shRNAs) in target cells.

transOMIC technologies can supply shRNAs targeting your lncRNA of interest*. These shRNAs contain the same features that make our gene-targeting shRNAs the best available.
  • Each shRNA targeting your lncRNA employs our shERWOOD shRNA design algorithm, resulting in superior knockdown performance
  • Each shRNA is provided in our UltramiR scaffold, increasing RNA processing and potency
  • Available in any of our lentiviral or retroviral shRNA vectors (inducible also available)
  • Glycerol stock and lentiviral particle formats available
Customer receives:
  • 3 top ranked shRNA targeting your lncRNA
  • Non-targeting control

*We can also target other non-coding RNAs. Request information

Knockdown lncRNA with our potent shRNA designs

Figure 1:  shRNAs designed against lncRNA provides sustained down-regulation of the target lncRNA,
making it effective for experiments trying to establish the function of lncRNAs.

How to order

Click the Request a Quote button to fill out the short form. Our specialists will contact you about your request within 24 hours to confirm your pricing request.

Learn more about available
RNAi Resources

View vector maps and sequences
for available shRNA vectors