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lncRNA Knockdown

lncRNA Knockdown Service

lncRNA knockdown is now possible with shERWOOD-UltramiR shRNA designs

Long non-coding RNAs (lncRNAs) are a type of non-coding RNAs (ncRNAs) that exceed 200 nucleotides in length. lncRNAs are involved in transcriptional regulation, post-transcriptional regulation events such as splicing and translation, epigenetic regulation and nucleation of protein complexes. Using a technique known as lncRNA knockdown, researchers are able to study lncRNA function by suppressing its expression and observing resulting phenotypes. The endogenous lncRNA expression can be down-regulated with an RNA silencing-mediated approach by stably expressing gene-specific RNA hairpins (shRNAs) in target cells.

transOMIC technologies can supply shRNAs targeting your lncRNA of interest*. These shRNAs contain the same features that make our gene-targeting shRNAs the best available.
  • Each shRNA targeting your lncRNA employs our shERWOOD shRNA design algorithm, resulting in superior knockdown performance
  • Each shRNA is provided in our UltramiR scaffold, increasing RNA processing and potency
  • Available in any of our lentiviral or retroviral shRNA vectors (inducible also available)
  • Glycerol stock and lentiviral particle formats available
Customer receives:
  • 3 top ranked shRNA targeting your lncRNA
  • Non-targeting control

*We can also target other non-coding RNAs. Request information

Knockdown lncRNA with our potent shRNA designs

Figure 1:  shRNAs designed against lncRNA provides sustained down-regulation of the target lncRNA,
making it effective for experiments trying to establish the function of lncRNAs.

How to order

Simply fill out the short form to request a quote. Our specialists will contact you about your request within 24 hours to confirm your pricing request.

Learn more about
shERWOOD-UltramiR shRNA designs

View vector maps and sequences
for available shRNA vectors