lncRNA knockdown is possible with shERWOOD-UltramiR shRNA designs
Long non-coding RNAs (lncRNAs) are a type of non-coding RNAs (ncRNAs) that exceed 200 nucleotides in length. lncRNAs are involved in transcriptional regulation, post-transcriptional regulation events such as splicing and translation, epigenetic regulation, and nucleation of protein complexes. Using a technique known as lncRNA knockdown, researchers are able to study lncRNA function by suppressing its expression and observing resulting phenotypes. The endogenous lncRNA expression can be down-regulated with an RNA silencing-mediated approach by stably expressing gene-specific RNA hairpins (shRNAs) in target cells.
Transomic Technologies can supply shRNAs targeting your lncRNA of interest*. These shRNAs contain the same features that make our gene-targeting shRNAs the best available.
- Each shRNA targeting your lncRNA employs our shERWOOD shRNA design algorithm, resulting in superior knockdown performance
- Each shRNA is provided in our UltramiR scaffold, increasing RNA processing and potency
- Available in any of our lentiviral or retroviral shRNA vectors (inducible also available)
- Glycerol stock and lentiviral particle formats available
- 3 top ranked shRNA targeting your lncRNA
- Non-targeting control
*We can also target other non-coding RNAs
Request information or a quote for lncRNA
Available vectors for your gene of interest
Inducible lentiviral vector