lncRNA knockdown



lncRNA knockdown is possible with shERWOOD-UltramiR shRNA designs

Long non-coding RNAs (lncRNAs) are a type of non-coding RNAs (ncRNAs) that exceed 200 nucleotides in length. lncRNAs are involved in transcriptional regulation, post-transcriptional regulation events such as splicing and translation, epigenetic regulation, and nucleation of protein complexes. Using a technique known as lncRNA knockdown, researchers are able to study lncRNA function by suppressing its expression and observing resulting phenotypes. The endogenous lncRNA expression can be down-regulated with an RNA silencing-mediated approach by stably expressing gene-specific RNA hairpins (shRNAs) in target cells.

Transomic Technologies can supply shRNAs targeting your lncRNA of interest*. These shRNAs contain the same features that make our gene-targeting shRNAs the best available.
  • Each shRNA targeting your lncRNA employs our shERWOOD shRNA design algorithm, resulting in superior knockdown performance
  • Each shRNA is provided in our UltramiR scaffold, increasing RNA processing and potency
  • Available in any of our lentiviral or retroviral shRNA vectors (inducible also available)
  • Glycerol stock and lentiviral particle formats available
Customer receives:
  • 3 top ranked shRNA targeting your lncRNA
  • Non-targeting control

*We can also target other non-coding RNAs

Request information or a quote for lncRNA





 

Available vectors for your gene of interest


Retroviral vectors

pLMN

pLMP-d


Lentiviral vectors

pZIP



Inducible lentiviral vector

pZIP TRE3G

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